Antibody-Drug Conjugates as Antifibrotic: Depleting Disease-Driving Cells
- Explore the use of single cell and spatial transcriptomics to identify pathogenic fibroblasts.
- Discuss the development of ADCs that selectively target pathogenic fibroblast populations driving fibrosis across organs
- Evaluate the translational potential of fibroblast-depleting ADCs across fibrotic diseases through various preclinical models.