Exploiting Extracellular Matrix–Myofibroblast Interactions to Selectively Eliminate Fibrosis-Driving Cells

3:00 pm - Thursday 3rd December 2026

  • Disrupting ECM-driven myofibroblast adhesion to promote selective myofibroblast apoptosis
  • Understanding how diseased ECM influences early fibrotic signalling & creates new therapeutic intervention points
  • Demonstrating activity across preclinical lung & kidney fibrosis models while assessing organ-specific ECM biology
  • Applying artificial intelligence (AI)-guided indication selection to identify where an early ECM-focused programme could deliver the greatest impact

Speakers:

Vice President - Research
aTyr Pharma Inc.