Generated Single-Cell and Spatial Atlases of Autopsy Tissue Samples from Donors who Died of COVID-19

Time: 8:30 am
day: Day One


• Hearing the integrated computational analysis uncovering substantial remodeling in the lung, with evidence of multiple paths of failed tissue regeneration
• Learning how viral RNAs were enriched in mononuclear phagocytic and endothelial lung cells, which induced specific host programs
• Exploring a spatial analysis in lung distinguished inflammatory host responses in lung regions with and without viral RNA
• Assessing how the analysis of the other tissue atlases showed transcriptional alterations in multiple cell types in heart tissue from donors with COVID-19