The “Free Choice” Diet-Induced Obese Hamster for Evaluating Drugs Targeting Nash & Fibrosis: A Promising Alternative to Mouse & Rat Models

Time: 11:30 am
day: Day 1 - Stream A - Morning


• Emphasizing the limitations of diet-induced mouse and
rat models for evaluation of drugs targeting NASH/liver
• Describing the free choice diet-induced obese hamster
as a preclinical model for NASH, liver fibrosis and
associated heart failure with preserved ejection fraction
• Presenting the effects of clinical benchmarks
demonstrating the relevance of the hamster model for
drug efficacy studies