Lee Borthwick
Seminars
Tuesday 18th November 2025
Enhancing Confidence in Candidates Through Human Precision-Cut Tissue Slices as a Preclinical Platform for Development & Testing of Anti- Fibrotic Therapeutics
12:00 pm
- Human precision-cut lung slices retain the cellular complexity and architecture of the native tissue in culture
- Established, dynamic models of tissue inflammation and fibrogenesis in precision-cut lung slices
- Application of PCLS for drug testing, target engagement and fibrogenesis in PCLS
