Exploring ADC-Mediated Depletion of Pathogenic Fibroblasts as a Therapeutic Strategy for Fibrosis
Time: 9:00 am
day: Day Two
Details:
- Highlighting the use of single-cell-based target discovery engines to identify and target specific pathogenic sub-populations of fibroblasts
- Examining the precision and specificity of identifying and targeting fibroblast subsets that drive fibrosis with antibody-drug conjugates
- Evaluating the effectiveness of these biologics in preclinical models of various fibrotic diseases, focusing on their sensitivity, specificity, and impact on disease-relevant endpoints