Leveraging Advanced Omics to Uncover Fibrotic Pathomechanisms & Identify Novel Approaches, Evaluate Biomarker Strategy, & Assess Antifibrotics in an Evolving Landscape to Cement Candidate Confidence
Since Madrigal’s Resmetirom secured the first-ever MASH approval in 2024, 2025 went on to deliver a wave of positive antifibrotic advances. United Therapeutics’ Phase 3 win, the FDA’s review of non-invasive endpoints for MASH, Boehringer’s Phase 3 IPF readout, Stanford’s TGF-β breakthroughs in cardiovascular fibrosis, and more than $3B in deals from Lilly and GSK collectively underscored how critical it had become for developers to demonstrate true differentiation-whether through novel targets, innovative biomarker strategies, or pan-fibrotic mechanisms.
These shared challenges were tackled head-on by 80+ leaders from Pfizer, Novartis, Gilead Sciences, and pioneering biotechs at the Antifibrotic Drug Development Summit - he only cross-fibrosis industry meeting uniting discovery through Phase 2 across IPF, MASH, kidney, cardiac, and systemic sclerosis fibrosis.
Attending Companies Include