From Exploring Shared Fibrosis Biology & Resolution Mechanisms to Evaluating Human-Relevant Models & Predictive Biomarkers: Navigate Cross-Indication Expansion with Confidence
With Celea Therapeutics raising $180 million towards its Phase 3 IPF programme, GRI Bio securing FDA Orphan Drug Designation and multiple differentiated assets advancing through clinical development, confidence in next-generation antifibrotic therapies continues to build. At the same time, advances in single-cell sequencing, spatial transcriptomics, human tissue models and predictive biomarkers are giving developers a more precise view of the cell states, tissue niches and pathways driving fibrosis.
Yet fibrosis is not one disease. Different organs begin with different injuries and microenvironments, while many programmes converge around shared processes. Understanding where these mechanisms are truly conserved, where tissue-specific biology changes the strategy and which lessons can be transferred from one indication to another is becoming increasingly important for target selection, model design, biomarker development and indication expansion.
Returning to Boston for its landmark 10th anniversary, the Antifibrotic Drug Development Summit is the only industry-focused forum dedicated to cross-indication antifibrotic drug development, uniting 60+ senior leaders across discovery, preclinical, translational, biomarker and early clinical development.
Joined by organizations including Madrigal Pharmaceuticals, AbbVie, Arda Therapeutics, aTyr Pharma and Vicore Pharma, the summit brings the wider fibrosis ecosystem together across three interactive workshops and two main conference days to compare approaches to fibrosis resolution, cross-tissue biology, human-relevant models, patient stratification and cross-indication expansion.
Gain the cross-organ insight, practical frameworks and industry connections needed to translate learning beyond your own indication, avoid siloed development decisions and advance more differentiated antifibrotic therapies towards clinical proof of concept.
Attending Companies Include